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Yasmin 21’s tablets – Contraceptive pill (birth control)

Yasmin tablet is a combined oral contraceptive used primary for family planning. It is also beneficial for women who experience hormone-related fluid retention and the resulting symptoms and for women with acne and seborrhea.
Each yasmin tablet contains; 0.03 mg ethinylestradiol (estrogen) and 3 mg drospirenone (progestin).

How to take Yasmin

Take one tablet starting on day 1 of the woman’s natural cycle (i.e. the first day of her menstrual bleeding) everyday at the same time.
Each subsequent pack is started after a 7-day tablet-free interval.

Management of missed tablets
If a woman is less than 12 hours late in taking any tablet, contraceptive protection is not reduced. The woman should take the tablet as soon as she remembers and should take further tablets at the usual time.
If she is more than 12 hours late in taking any tablet, contraceptive protection may be reduced.

In case of severe gastro-intestinal disturbances or vomiting occurs within 3-4 hours after tablet-taking yasmin absorption may not be complete and additional contraceptive measures should be taken.

Side Effects

Common:
Nausea, breast pain, unscheduled uterine bleeding.

Serious:
Venous/arterial thromboembolism (e.g., DVT, pulmonary embolism, stroke, myocardial infarction),liver tumors, hypertension and gallbladder disease.

Rare:
Mood changes, migraines, hypersensitivity (rash, urticaria), hyperkalemia (in renal impairment).

Precautions

Yasmin is contraindicated in the following conditions;

History of thrombosis, severe hepatic/renal disease, hormone-sensitive cancers, undiagnosed vaginal bleeding, pregnancy, or hypersensitivity.

Warnings:
  • With yasmin there is increased thrombosis risk with smoking, obesity, hypertension or prolonged immobilization
  • Monitor for breast cancer, liver dysfunction, and potassium levels in renal impairment is recommended with prolonged use of yasmin.
  • Taking yasmin may worsen conditions like lupus, porphyria, or cholestasis.

Interactions

  • Enzyme inducers  e.g. rifampicin, carbamazepine reduces the efficacy of yasmin.
  • Enzyme inhibitors e.g. ketoconazole, grapefruit juice increases plasma concentration of yasmin thus likelihood of yasmin side effects.
  • There is hyperkalemia risk with concommitant use of potassium-sparing diuretics, ACE inhibitors.

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