Indications of Mercaptopurine:
- Acute lymphoblastic leukemia (ALL)
- Acute myeloid leukemia (AML) – as part of combination therapy
- Other hematologic cancers as directed by a hematologist/oncologist
How to take mercaptopurine:
- Oral use only
- Usual dose is calculated by the doctor based on body surface area, treatment protocol, and patient condition
- Tablets should be swallowed whole with water, preferably on an empty stomach (at least 1 hour before or 2 hours after food)
- Regular blood tests are essential to monitor blood counts and liver function
Safety Information:
- Contraindicated in patients with known hypersensitivity to mercaptopurine or thioguanine
- Common side effects: nausea, vomiting, diarrhea, mouth sores, loss of appetite, fatigue
- Serious risks: bone marrow suppression (low blood counts), liver toxicity, increased infection risk, pancreatitis
- Long-term use may increase the risk of secondary cancers
- Use with caution in patients with TPMT (thiopurine methyltransferase) enzyme deficiency – dose adjustments may be needed
- Effective contraception is recommended during and after treatment, as mercaptopurine may harm the unborn child
Notice:
Mercaptopurine 50mg Tablets are a prescription-only cytotoxic medicine. They should only be used under the supervision of an oncologist or hematologist with regular monitoring.
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