Bifril Plus combines zofenopril, an ACE inhibitor, with hydrochlorothiazide, a thiazide diuretic. Together, they lower blood pressure by relaxing blood vessels and promoting the removal of excess salt and water from the body.
This combination is indicated for adults whose blood pressure remains uncontrolled on zofenopril monotherapy. Consistent blood pressure management helps reduce the risk of stroke, heart attack, kidney disease, and other cardiovascular complications.
Uses
- Treatment of mild to moderate essential hypertension requiring combination therapy
Active Ingredients
- Zofenopril calcium 30 mg
- Hydrochlorothiazide 12.5 mg
How to Take
- Take one tablet once daily as prescribed.
- May be taken with or without food.
- Swallow whole with water.
Precautions
- Prescription-only medicine.
- Do not use during pregnancy.
- Monitor kidney function, electrolytes, and blood pressure.
- Use cautiously in patients with renal impairment or dehydration.


